Keys noted that the earliest manufacture of wine took place around 8000 BC. Robinson (2006) said that Pliny the Elder remarked that wine adulteration had reached a point in 1st century Rome that wine was no longer worth drinking. Although the tinkering with the grape has been with us since early Rome, wine fraud cases have seen an upsurge due to increases in demand not only for wine for the family table wine, but for historic collectibles found in the cellars of the wine connoisseur (Robinson, 2006). Wine fakers cost consumers, suppliers, and collectible connoisseurs millions of dollars a year. They use humidification; blending and stretching; substitution of low quality for expensive quality; and many other forms of fakery. This fakery is not only costly to the consumer but has led to cases of serious injury and death (Henry, 1986). This article addresses the fakes, how they are processed, and forensic applications used to detect and indentify the bogus mix.